| ABI3 Rabbit mAb |
| LTA24750 |
| 100ul |
|
$750
In stock
|
| This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. |
| NESH; SSH3BP3 |
| 51225,ABI3,NESH,SSH3BP3,ABI family member 3,ABI gene family member 3,new molecule including SH3,Q9P2A4,ABI Family Member 3,New Molecule Including SH3,ABI Gene Family Member 3,ABI Family,Member 3,Nesh |
| Human |
| 51225 |
| Q9P2A4 |
| VPDGRLSAAS SAFSLASAGS AEGVGGAPTP KGQAAPPAPP LPSSLDPPPP PAAVEVFQRP PTLEELSPPP PDEELPLPLD LPPPPPLDGD ELGLPPPPPG FGPDEPSWVP ASYLEKVVTL YPYTSQKDNE LSFSEGTVIC VTRRYSDGWC EGVSSEGTGF FPGNYVEPSC |
| Recombinant fusion protein containing a sequence corresponding to amino acids 197-366 of human ABI3 (NP_057512.2). |
| Rabbit |
| Affinity Purified Monoclonal IgG |
| WB, ELISA |
| Human |
| 39kDa |
| WB,1:1000 - 1:4000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements. |
|
Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.
|
|
Shipped at ambient temperature.
|
|
Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.
|
|
Western blot analysis of various lysates using ABI3 Rabbit mAb (LTA24750) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Negative control (NC): Hep G2|Exposure time: 45s. |