ABI3 Rabbit mAb

Product Name
ABI3 Rabbit mAb
Catalog Number
LTA24750
Quantity
100ul
Price
$750 In stock
Description
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants.
Alias
NESH; SSH3BP3
Keywords
51225,ABI3,NESH,SSH3BP3,ABI family member 3,ABI gene family member 3,new molecule including SH3,Q9P2A4,ABI Family Member 3,New Molecule Including SH3,ABI Gene Family Member 3,ABI Family,Member 3,Nesh
Gene Template Species
Human
Gene/Protein ID
51225
SWISS ID
Q9P2A4
Antigen Sequence
VPDGRLSAAS SAFSLASAGS AEGVGGAPTP KGQAAPPAPP LPSSLDPPPP PAAVEVFQRP PTLEELSPPP PDEELPLPLD LPPPPPLDGD ELGLPPPPPG FGPDEPSWVP ASYLEKVVTL YPYTSQKDNE LSFSEGTVIC VTRRYSDGWC EGVSSEGTGF FPGNYVEPSC
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 197-366 of human ABI3 (NP_057512.2).
Animal Source
Rabbit
Antibody Type
Affinity Purified Monoclonal IgG
Applications
WB, ELISA
Cross-Reactivity
Human
Molecular Weight
39kDa
Recommended Dilution
WB,1:1000 - 1:4000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements.
Stability and Storage

Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.

Image
 ABI3 Rabbit mAb

Western blot analysis of various lysates using ABI3 Rabbit mAb (LTA24750) at 1:1000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Negative control (NC): Hep G2|Exposure time: 45s.

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