Selected Publications

Selected Publications and Success Stories

LifeTein provides custom peptide synthesis, custom chemical synthesis, and antibody products and services to support academic, government, pharmaceutical, and biotech research. This page highlights selected examples in which LifeTein products or services were cited in peer-reviewed publications, with emphasis on technically demanding peptide formats and research-driven applications.

Featured Capabilities Demonstrated in Publications

  • Long peptide synthesis
  • Fluorescent peptide labeling
  • N-terminal acetylation
  • C-terminal amidation
  • Ahx spacer incorporation
  • Phosphopeptides and PTM-containing peptides
  • Biotinylated and linker-modified peptides
  • Cyclic and constrained peptide formats
  • Peptide-based antibody generation

Selected Publications and Case Studies

These examples illustrate capabilities such as long peptide synthesis, fluorescent labeling, phosphopeptides, cyclic peptides, linker-modified peptides, and peptide tools used in antibody and mechanistic studies.

PNAS: FITC-labeled nuclear receptor interaction peptide

PNAS • 2019

LifeTein synthesized a peptide containing an LXXLL motif with an N-terminal FITC label, a six-carbon linker (Ahx), and an amidated C-terminus for structural and receptor agonism studies.

Fluorescent peptide Ahx linker Amidated peptide

Cell: Cell-penetrating scorpion toxin and labeled peptide variants

Cell • 2019

This work used multiple advanced peptide formats synthesized by LifeTein, including toxin variants, biotinylated peptide variants, and Alexa Fluor-labeled peptide constructs.

Labeled peptide Biotin peptide CPP-related

Nature Communications: Coregulator peptide with biotin label and amidated C-terminus

Nature Communications • 2018

LifeTein synthesized an NCoR1-derived peptide containing an N-terminal biotin label and an amidated C-terminus for receptor and structural studies.

Biotinylated peptide End-modified peptide

Nature: Phosphorylated peptides used for phospho-specific antibody studies

Nature • 2013

LifeTein designed and synthesized phosphorylated peptides that were then used for phospho-specific antibody production and validation.

Phosphopeptide Antibody-related

Cell: Cyclic peptide used in HIV-1 integrase study

Cell • 2016

A constrained cyclic peptide format synthesized by LifeTein was used in virology and structural biology work, illustrating capability in non-linear peptide architectures.

Cyclic peptide Constrained peptide

Selected recent literature citing LifeTein

These examples are compiled from publicly available literature and are updated periodically. Many additional studies have used LifeTein materials but may not be included in this list.

Related pages

For more peptide-focused examples, see Publication-Grade Peptides: Selected Examples from the Literature. For service pages connected to these capabilities, see Long Peptide Synthesis, FITC Peptide Synthesis, and Peptide Synthesis Services.