Custom Peptide Synthesis Services

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1. Please click here to receive a quote now!

2. If you have a quote number already, please click here to place an order now!

LifeTein^® is a custom peptide synthesis service company that has developed a proprietary technology called PeptideSyn^TM. This technology uses Fmoc and Boc chemistry, a special solid support resin, and microwave technology to provide a platform for continuous peptide synthesis. One of the many advantages of this technology is that it allows LifeTein to offer competitive pricing.

LifeTein has extensive experience in using microwave technologies to synthesize peptides, including peptides that are over 100 amino acids long. Our notable achievements include a 76aa BfUbb peptide, a 97aa peptide mB Box-97syn, a 133aa SHT peptide, and a 169aa long peptide. We guarantee that all the peptides are HPLC-purified and have the correct molecular weight, as confirmed by Electrospray Ionization (ESI) Mass Spectrometry analysis.

LifeTein offers a wide range of peptides with different types of special modifications, such as Peptide Oligo Conjugate by Click Chemistry, Stapled Peptide, Lipid Nanoparticles, Stable Isotope Labeled Peptides, Peptide Nucleic Acids, Fluorescent Peptide: Cy3/Cy5/Cy7, Phosphorylated Peptide, Glycosylation, Peptide pool service, Biotinylated Peptides, Cell-Permeable Peptide, Cyclic Peptide, Long Peptide Synthesis (up to 169 amino acids), MAP Peptide Synthesis, and D Amino Acid Peptide.

Click here to see the full list of modifications.

References:

NUCLEIC ACID VECTORS AND USES THEREOF: LifeTein synthesized a peptide of 133 amino acids. The peptide sequence includes at least one cell-permeable peptide (CPP) domain, one secretion signal sequence, one DNA binding domain, and other SHT protein.

You might be interested in this article: How Do Peptides Fold?

Tip: How to detect small peptide clearly and sensitively by Western blotting or SDS-PAGE?

Phosphorylation: Posttranslational modification on Tyr, Ser and Thr residues, signal transduction, gene expression and protein-protein interaction

Biotinylation: Strong affinity for streptavidin and avidin to be used in histocytochemistry, immunoassays, and fluorescence based flow cytometry

Cyclization: Peptides can be cyclized by disulfide bond, head-to-tail, amide or thioester cyclization to stabilize the peptide conformation, increase bioactivity, and enzyme stability

Long Peptide Synthesis: An alternative approach to exogenous protein expression

Cell Permeable Peptides: Deliver biologically active cargo to the cell interior; Enter the plasma membrane of a cell independent of a membrane receptor

Linker, Spacer, PEGylations: Reduce steric hindrance at the binding sites of the peptide and improve proteolytic stability and solubility of peptides

fluorescent labelings: FITC, FAM, TAMRA, Rhodamine, Dansyl, 4-Dinitrophenyl (Dnp), 7-methoxycoumarin acetic acid (Mca) Cy3, Cy5, Cy7 for Fluorescence based assays, flow cytometry, protein-protein interaction, and localization studies

Short Peptide Synthesis: dipeptides or tripeptides as the ligands for signal transduction or cosmetic applications

D Amino Acid Peptides: Resistant to proteases for higher stability and special structure for peptide drug design

TFA Free Acetate Peptides: Low toxic peptides for peptide drug and cell studies

Rush Peptide Service: Receive your peptides in a week and accelerate your research

Peptide Magnetic Agarose Conjugate: Conjugate your peptide to the magnetic agarose for easy binding assay

N Terminal Acetylation: Increase peptide stability by preventing N and C-terminal degradation.

C Terminal Amidation: Neutralize negative charge created by the C-terminal COOH. Mimic native proteins, and remove hydrogen bonding which may interfere with the assays

Multiple Antigenic Peptides (MAP), Dendrimers and Dendrons: Branched peptides MAP4 or MAP8 have a high molar ratio of the peptide antigen for higher immune responses

Immunogenic Peptides: BSA, KLH or OVA Conjugation: Conjugated peptides for ELISA, antibody production applications

Peptide Library: Large scale of peptide screening for new drug candidates

Stapled Peptide, Glycosylation, and Special Amino Acids: Palmitic acid increases the cell permeability and helps the binding of the peptides to a cell membrane.

FRET Peptides

Disulfide Bond Peptides

Features and Benefits

FREE aliquoting is available. Why aliquot?
TFA removal service. Why remove TFA?
Free peptide online analysis tool: Analyze my peptides
Peptide quantities from mg to kg
Sequence lengths of 2-170 amino acids
Peptide purity levels including crude, desalted, >75%, >85%, >95%, 98%, and greater than >99%
Comprehensive range of peptide modifications: KLH, CPP tag, Cy3, Cy5, Cy7, Oligonucleotide, Stapled peptides, Glycosylation, Magnetic Agarose, and biotin. Click here to see the full list of modifications
Fast turnaround: most peptides synthesized can be delivered within 2-3 weeks
Peptide library service options
Stringent analytical specifications including free HPLC and MS analyses
Peptides are sealed to prevent oxidation. Why seal peptides?
D amino acid peptides can be synthesized to resist common proteases.

Try our custom peptide synthesis service and read what our customers have to say:

Choose high-quality peptides: Get published in Nature.
Large capacity: We have the capacity to produce 5,000 purified peptides per month, ranging from crude to highly pure and complex peptides.
Guaranteed quality: Peptide synthesis projects are carried out by using Fmoc and Boc chemistry under strict quality control based on HPLC and by mass spectrometry. 95% of all projects are finalized in 2-3 weeks to guarantee on-time delivery.
Data protection: All sequences supplied to LifeTein^® are considered to be the confidential property of the customer. LifeTein^® hereby disclaims any rights whatsoever to any intellectual property or information provided by the customer, including materials or any peptide sequences. At the completion of the project, all synthetic peptides that meet the purity criteria will be sent to the customer.

Frequently Asked Questions: Peptide Synthesis

How should I store and handle the synthesized peptides?
How should I dissolve peptides?
What is net peptide content?
How do I detect small peptides using SDS-PAGE?
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CPP Peptide Synthesis

The process of introducing medicines into cells has always proved to be a major challenge for scientists. However, CPPs have the ability to enter a cell through the plasma membrane independent of a membrane receptor. They are usually small peptides 10-30 residues in length.

Stapled Peptide Synthesis Service

Click here or picture below for details.

cell permeable peptide synthesis service

The following table shows a selection of currently known CPPs, together with their origins and sequences. Click here for more details.Check more for case studies.

Name	Sequence
HIV-1 protein	GRKKRRQRRRPPQQ
Stearyl-R8	Stearly-RRRRRRRR-amide order this peptide now! FITC-Stearyl-R8 Control peptide

How to estimate prices and place orders for custom peptide synthesis:

Please fax our order form to 1-888-791-1618 or email us at peptide@lifetein.com

1. You can use the following table to estimate peptide synthesis price. Please inquire for more pricing information:

Custom peptide synthesis Pricing Examples
(Prices are per amino acid, and are valid for peptides up to 30 residues. Get a quote for peptides sized 30 to 200 residues. )

Quantity		Purity
Quantity	Crude	>85% (Get a quote for desalted, 75%, 80% and other purities)	>95% (Get a quote for >98%, 99% and other purities)
1-4 mg (Get a quote for 5-9mg, 10-14mg and other quantities )	$3.20	$9.00	$11.56
15-20 mg	$4.76	$15.30	$20.40
40-50 mg	$6.46	$19.89	$27.20
70-80 mg	$7.82	$26.69	$35.70
1000 mg	$28.05	$79.90	$105.40

Click here to see the list of available peptide modifications

Our standard peptide synthesis package includes a certificate of analysis, and HPLC and MS reports.
Amino Acid Analysis and N Elemental Analysis are available at competitive prices.
Free peptide aliquoting services are available.
Solubility tests are available.
TFA removal service is available.
Discounts are offered for large orders.
The turnaround time for regular peptide synthesis services is 2-3 weeks.
Shipping price: $35.00 (U.S.), $65.00 (International).

2. Quotations

Method 1: Obtain a quote using the online quotation form:

Method 2: Please complete the Quotation Form for the peptide(s) you would like to purchase and either fax it to 1-888-791-1618 or email it to peptide@lifetein.com. We will send you a formal quote within 24 hours.

3. Placing an order

Method 1: Place your order online if you already have a quote number:

Method 2: Please sign the quote form we send you, and either fax it to 1-888-791-1618 or email it with your Purchase Order, if applicable, to peptide@lifetein.com. We will confirm your order within 24 hours.