Annexin A6/Annexin VI Rabbit mAb

Product Name
Annexin A6/Annexin VI Rabbit mAb
Catalog Number
LTA24715
Quantity
100ul
Price
$750 In stock
Description
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
Alias
p68; p70; ANX6; CBP68; CPB-II
Keywords
309,sc-30763,sc-1931,sc-30764,sc-11388,67 kDa calelectrin,Annexin 6,annexin A6,Annexin VI,ANX6,ANXA6,Calphobindin II,CBP68,Chromobindin 20,CPB II,Lipocortin VI,p68,p70,Protein III,CPB-II,annexin VI (p68),annexin-6,calcium-binding protein p68,calelectrin,calphobindin II,chromobindin-20,lipocortin VI,testis secretory sperm-binding protein Li 198a,P08133,Annexin A6,67 KDa Calelectrin,Chromobindin-20,Annexin-6,P68,P70,Testis Secretory Sperm-Binding Protein Li 198a,Calcium-Binding Protein P68,Annexin VI (P68),Calphobindin-II,Calelectrin
Gene Template Species
Human
Gene/Protein ID
309
SWISS ID
P08133
Antigen Sequence
DDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLKALLALCGGED
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 324-673 of human Annexin A6/Annexin VI (NP_001146.2).
Animal Source
Rabbit
Antibody Type
Affinity Purified Monoclonal IgG
Applications
WB, ELISA
Cross-Reactivity
Human, Mouse, Rat
Molecular Weight
76kDa
Recommended Dilution
WB,1:23000 - 1:138000|ELISA,Recommended starting concentration is 1 _g/mL. Please optimize the concentration based on your specific assay requirements.
Stability and Storage

Reconstituted antibodies stable at -80C for 12 months, 4C for 1 week. Avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Dissolve the lyophilized antibodies in distilled water. 5-10% glycerol is recommended.

Image
 Annexin A6/Annexin VI Rabbit mAb

Western blot analysis of various lysates using Annexin A6/Annexin VI Rabbit mAb (LTA24715) at 1:23000 dilution incubated overnight at 4_.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (LT014) at 1:10000 dilution.|Lysates/proteins: 25 _g per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (LT00020).|Exposure time: 10s.

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