| Our HIV Strain V2 Peptide, with the sequence AVGLGAVF, is a crucial tool in the advancement of HIV-1 vaccine development, particularly in the context of eliciting broadly neutralizing antibody responses. This peptide is derived from the fusion peptide (FP) of the HIV-1 Env gp41 subunit, a key target for broad immune recognition in vaccine strategies.
Key Features:
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Critical in HIV-1 Vaccine Research: The V2 peptide is instrumental in studying the interaction of antibodies with the fusion peptide of HIV-1, a major target for vaccine development.
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High Relevance to Broad Neutralization: This peptide aids in understanding how antibodies can broadly neutralize diverse HIV-1 strains, a crucial aspect of effective vaccine design.
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Insight into Antibody Binding Dynamics: The AVGLGAVF sequence is essential for studying the binding behavior of antibodies and their affinity to different FP sequences, providing insights into the energetics of antibody-peptide interactions.
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Facilitates Vaccine Efficacy Studies: The peptide is vital for research aiming to improve the neutralization breadth of anti-FP vaccines and antibodies against HIV-1.
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Supports Advanced Vaccine Strategies: Research with this peptide contributes to the development of prime-boost immunization strategies that elicit broad antibody responses against HIV-1.
Applications:
- HIV-1 Vaccine Development: Essential for creating vaccines that elicit broadly neutralizing antibodies against diverse HIV-1 strains.
- Antibody Research: Useful in studying the binding dynamics and energetics of antibodies targeting the HIV-1 FP.
- Neutralization Breadth Analysis: Aids in evaluating and enhancing the breadth of neutralizing responses elicited by HIV-1 vaccines.
Quality Assurance:
Our HIV Strain V2 Peptide is synthesized with precision, ensuring high purity and consistency. Each batch undergoes rigorous quality control and is accompanied by a comprehensive Certificate of Analysis.
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