| Biotinylated Cynomolgus MSLN/Mesothelin Protein (Primary Amine Labeling) (LTP10699) |
| LTP10699 |
| 100ug |
|
$789 In stock |
| Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally. |
| Recombinant Biotinylated Cynomolgus MSLN/Mesothelin Protein (Primary Amine Labeling) is expressed from Expi293 with His tag at the C-terminal. It contains Asp296-Gly580. |
| MSLN/Mesothelin |
| Cynomolgus |
| A0A2K5TW94-1 |
| Asp296-Gly580 |
| The protein has a predicted MW of 33 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on the Tris-Bis PAGE result. |
| Immobilized Anti-MSLN Antibody, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Cynomolgus MSLN, His Tag with the EC50 of 54.8ng/ml determined by ELISA. See testing image for detail. |
| C-His |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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