Biotinylated Human AXL Protein (LTP11094)

Product Name
Biotinylated Human AXL Protein (LTP11094)
Catalog Number
LTP11094
Quantity
100ug
Price
$789 In stock
Background
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
Description
Recombinant Biotinylated Human AXL Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Ala26-Pro449.
Target
AXL
Species
Human
Gene/Protein ID
P30530-1
Exact Sequence
Ala26-Pro449
Molecular Weight
The protein has a predicted MW of 48.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Anti-AXL Anitibody at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human AXL, His Tag with the EC50 of 0.87ug/ml determined by ELISA. See testing image for detail.
Tag
C-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Biotinylated Human AXL Protein (LTP11094)
  • 5 Units in Stock

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