Biotinylated Human CD20/MS4A1 Protein (LTP10588)

Product Name
Biotinylated Human CD20/MS4A1 Protein (LTP10588)
Catalog Number
LTP10588
Quantity
100ug
Price
$789 In stock
Background
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.
Description
Recombinant Biotinylated Human CD20/MS4A1 Protein is expressed from E.coli with His tag and Avi tag at the C-terminal. It contains Ile141-Ser188.
Target
CD20/MS4A1
Species
Human
Gene/Protein ID
P11836-1
Exact Sequence
Ile141-Ser188
Molecular Weight
The protein has a predicted MW of 16.8 kDa same as Tris-Bis PAGE result.
Activity
Immobilized Biotinylated Human CD20, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD20 Antibody, hFc Tag with the EC50 of 87.3ng/ml determined by ELISA. See testing image for detail.
Tag
C-His-Avi
Express System
E.coli
Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Supplied as 0.22 um filtered solution in 20mM PB ,10% glycerol (pH 7.0). Please dilute to the desired concentration according to the concentration of the solution shown on the product label.
Stability and Storage

Valid for 12 months from date of receipt when stored at -80 C.? Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.

Shipping
Shipped with blue ice.
Reconstitution

0

Image
Biotinylated Human CD20/MS4A1 Protein (LTP10588)
  • 5 Units in Stock

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