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| Biotinylated Human CD79B Protein (LTP10883) |
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| LTP10883 |
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| 100ug |
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$789 In stock |
| CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 36-40 kDa member of the Ig-Superfamily. It is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. |
| Recombinant Biotinylated Human CD79B Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Ala29-Asp159. |
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| CD79B |
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| Human |
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| P40259-1 |
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| Ala29-Asp159 |
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| The protein has a predicted MW of 18.1 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Anti-CD79B Antibody, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human CD79B, His Tag with the EC50 of 23.3ng/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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