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| Biotinylated Human FGFR1 beta (IIIc) Protein (LTP10009) |
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| LTP10009 |
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| 100ug |
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$789 In stock |
| Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. |
| Recombinant Biotinylated Human FGFR1 beta (IIIc) Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Lys158-Thr355. |
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| FGFR1 beta (IIIc) |
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| Human |
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| P11362-7 |
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| Lys158-Thr355 |
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| The protein has a predicted MW of 25.23 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Anti-FGFR1 Anitibody at 5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human FGFR1 beta (IIIc) , His Tag with the EC50 of 0.35ug/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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