| Biotinylated Human FGFR2 alpha (IIIb) Protein (LTP11037) |
| LTP11037 |
| 100ug |
|
$789 In stock |
| Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. |
| Recombinant Biotinylated Human FGFR2 alpha (IIIb) Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Arg22-Glu378. |
| FGFR2 alpha (IIIb) |
| Human |
| P21802-3 |
| Arg22-Glu378 |
| The protein has a predicted MW of 42.5 kDa. Due to glycosylation, the protein migrates to 70-110 kDa based on the Tris-Bis PAGE result. |
| Immobilized Anti-FGFR2 alpha (IIIb) Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human FGFR2 alpha (IIIb) , His Tag with the EC50 of 18.7ng/ml determined by ELISA. See testing image for detail. |
| C-His-Avi |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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