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| Biotinylated Human KRAS G12V (HLA-A*02:01) Protein (LTP10000) |
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| LTP10000 |
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| 100ug |
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$650 In stock |
| Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on the sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. |
| Recombinant Biotinylated Human HLA-A*02:01, Ile21-Met119(B2M), KRAS G12V (KLVVVGAVGV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLVVVGAVGV peptide. |
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| KRAS G12V (HLA-A*02:01) |
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| Human |
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| A0A140T913(HLA-A*02:01)&P61769(B2M)&KLVVVGAVGV |
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| Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLVVVGAVGV peptide |
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| The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Tris-Bis PAGE result. |
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| The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Tris-Bis PAGE result. |
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| C-His-Avi |
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| E.coli |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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