| Biotinylated Human MICA Protein (LTP11106) |
| LTP11106 |
| 100ug |
|
$789 In stock |
| TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig?like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin. |
| Recombinant Biotinylated Human MICA Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Glu24-Gln308. |
| MICA |
| Human |
| Q96QC4 |
| Glu24-Gln308 |
| The protein has a predicted MW of 35.8 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on the Tris-Bis PAGE result. |
| Immobilized Human NKG2D, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human MICA, His Tag with the EC50 of 0.32ug/ml determined by ELISA (QC Test). See testing image for detail. |
| C-His-Avi |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Biotinylated Human MICA Protein (LTP11106)](/peptide-product/images/protein-products/LTP11106/20220826144206.png) |