|
| Cynomolgus B7-1/CD80 Protein (LTP10640) |
|
| LTP10640 |
|
| 100ug |
|
|
$360 In stock |
| Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. |
| Recombinant Cynomolgus B7-1/CD80 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Val35-Asn242. |
|
| B7-1/CD80 |
|
| Cynomolgus |
|
| G7NXN7 |
|
| Val35-Asn242 |
|
| The protein has a predicted MW of 25 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on the Tris-Bis PAGE result. |
|
| The affinity constant of 9.90 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
|
| C-His |
|
| Expi293 |
|
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
|
| Less than 1EU per ug by the LAL method. |
|
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
|
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
| Shipped at ambient temperature. |
|
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
|
|  |
