Cynomolgus B7-H6/NCR3LG1 Protein (LTP10604)

Product Name
Cynomolgus B7-H6/NCR3LG1 Protein (LTP10604)
Catalog Number
LTP10604
Quantity
100ug
Price
$406 In stock
Background
B7-H6 is a glycosylated member of the B7 family of immune co?stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.
Description
Recombinant Cynomolgus B7-H6/NCR3LG1 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Asp25-Asp259.
Target
B7-H6/NCR3LG1
Species
Cynomolgus
Gene/Protein ID
XP_005578557.1
Exact Sequence
Asp25-Asp259
Molecular Weight
The protein has a predicted MW of 27.6 kDa. Due to glycosylation, the protein migrates to 40-52 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 0.662 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Cynomolgus B7-H6/NCR3LG1 Protein (LTP10604)
  • 5 Units in Stock

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