Cynomolgus BAFFR/TNFRSF13C Protein (LTP10719)

Product Name
Cynomolgus BAFFR/TNFRSF13C Protein (LTP10719)
Catalog Number
LTP10719
Quantity
100ug
Price
$473 In stock
Background
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
Description
Recombinant Cynomolgus BAFFR/TNFRSF13C Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ser7-Ala71.
Target
BAFFR/TNFRSF13C
Species
Cynomolgus
Gene/Protein ID
XP_001101623.2
Exact Sequence
Ser7-Ala71
Molecular Weight
The protein has a predicted MW of 7.7 kDa. Due to glycosylation, the protein migrates to 13-25 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Cynomolgus BAFFR, His Tag at 1ug/ml (100ul/Well) on plate.Dose response curve for Anti-BAFFR Ab., hFc Tag with the EC50 of 11.1ng/ml determined by ELISA. See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Cynomolgus BAFFR/TNFRSF13C Protein (LTP10719)
  • 5 Units in Stock

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