| Cynomolgus LILRB2/CD85d/ILT4 Protein (LTP10183) |
| LTP10183 |
| 100ug |
|
$473 In stock |
| The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. |
| Recombinant Cynomolgus LILRB2/CD85d/ILT4 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Gly24-Arg457. |
| LILRB2/CD85d/ILT4 |
| Cynomolgus |
| XP_015297203.1 |
| Gly24-Arg457 |
| The protein has a predicted MW of 71.68 kDa. Due to glycosylation, the protein migrates to 80-90 kDa based on the Tris-Bis PAGE result. |
| The affinity constant of 42.50 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
| C-hFc |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Cynomolgus LILRB2/CD85d/ILT4 Protein (LTP10183)](/peptide-product/images/protein-products/LTP10183/20230317153627.png) |