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| Cynomolgus TIGIT Protein (LTP10561) |
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| LTP10561 |
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| 100ug |
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$406 In stock |
| TIGIT, also called Vstm3, Vsig9, and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins.IGIT is expressed at low levels on peripheral memory and regulatory CD4 T-cells and NK cells and is up-regulated following activation of these cells. |
| Recombinant Cynomolgus TIGIT Protein is expressed from Expi293 with His tag at the C-terminal. It contains Met89-Ile208. |
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| TIGIT |
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| Cynomolgus |
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| XP_015300911.1 |
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| Met89-Ile208 |
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| The protein has a predicted MW of 14.4 kDa. Due to glycosylation, the protein migrates to 18-25 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Cynomolgus TIGIT, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TIGIT Antibody, hFc Tag with the EC50 of 30.3ng/ml determined by ELISA. See testing image for detail. |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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