Cynomolgus/Rhesus macaque 4-1BB/TNFRSF9 Protein (LTP10622)
LTP10622
100ug
$ 406 In stock
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. Recombinant Cynomolgus/Rhesus macaque 4-1BB/TNFRSF9 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Leu24-Gln186.
4-1BB/TNFRSF9
Cynomolgus/Rhesus macaque
XP_005544945.1
Leu24-Gln186
The protein has a predicted MW of 18.4 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on the Tris-Bis PAGE result.
Immobilized Cynomolgus/Rhesus macaque 4-1BB, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Cynomolgus 4-1BB Ligand, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA. See testing image for detail.
C-His
Expi293
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Less than 1EU per ug by the LAL method.
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Shipped at ambient temperature.
Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.