| Cynomolgus/Rhesus macaque CD27/TNFRSF7 Protein (LTP10586) |
| LTP10586 |
| 100ug |
|
$473 In stock |
| CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co?stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. |
| Recombinant Cynomolgus/Rhesus macaque CD27/TNFRSF7 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Ala20-Arg191. |
| CD27/TNFRSF7 |
| Cynomolgus/Rhesus macaque |
| XP_005569963.1 |
| Ala20-Arg191 |
| The protein has a predicted MW of 46.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
| Immobilized Cynomolgus CD27 Ligand, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque CD27, hFc Tag with the EC50 of 70.8ng/ml determined by ELISA. See testing image for detail. |
| C-hFc |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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