Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone; Glucagon-like peptide 1 (GLP-1) is a potent stimulator of glucose-dependent insulin release and plays important roles on gastric motility and the suppression of plasma glucagon levels; The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2. Those peptides result from selective cleavage of the proglucagon molecule. | 