| Human B7-H7/HHLA2 Protein (LTP10264) |
| LTP10264 |
| 100ug |
|
$406 In stock |
| B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
| Recombinant Human B7-H7/HHLA2 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Ile23-Asn344. |
| B7-H7/HHLA2 |
| Human |
| Q9UM44-1 |
| Ile23-Asn344 |
| The protein has a predicted MW of 63.7 kDa. Due to glycosylation, the protein migrates to 78-100 kDa based on the Tris-Bis PAGE result. |
| Immobilized Human CD28H, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human B7-H7, hFc Tag with the EC50 of 52.7ng/ml determined by ELISA (QC Test). The affinity constant of 334 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
| C-hFc |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Human B7-H7/HHLA2 Protein (LTP10264)](/peptide-product/images/protein-products/LTP10264/20211111173833.png) |