| Human BAFFR/TNFRSF13C Protein (LTP10839) |
| LTP10839 |
| 100ug |
|
$519 In stock |
| BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF. |
| Recombinant Human BAFFR/TNFRSF13C Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ser7-Ala71. |
| BAFFR/TNFRSF13C |
| Human |
| Q96RJ3-1 |
| Ser7-Ala71 |
| The protein has a predicted MW of 7.6 kDa. Due to glycosylation, the protein migrates to 13-25 kDa based on the Tris-Bis PAGE result. |
| Immobilized Human BAFFR, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Anti-BAFFR Antibody, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA. The affinity constant of 1.21 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
| C-His |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Human BAFFR/TNFRSF13C Protein (LTP10839)](/peptide-product/images/protein-products/LTP10839/20220308123150.png) |