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| Human BAFFR/TNFRSF13C Protein (LTP10839) |
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| LTP10839 |
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| 100ug |
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$519 In stock |
| BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF. |
| Recombinant Human BAFFR/TNFRSF13C Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ser7-Ala71. |
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| BAFFR/TNFRSF13C |
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| Human |
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| Q96RJ3-1 |
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| Ser7-Ala71 |
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| The protein has a predicted MW of 7.6 kDa. Due to glycosylation, the protein migrates to 13-25 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human BAFFR, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Anti-BAFFR Antibody, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA. The affinity constant of 1.21 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| C-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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