Human CCR8 Protein (LTP10029)

Product Name
Human CCR8 Protein (LTP10029)
Catalog Number
LTP10029
Quantity
100ug
Price
$473 In stock
Background
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.
Description
Recombinant Human CCR8 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Met1-Lys35.
Target
CCR8
Species
Human
Gene/Protein ID
P51685-1
Exact Sequence
Met1-Lys35
Molecular Weight
The protein has a predicted MW of 30.62 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human CCR8, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CCR8 Antibody, hFc Tag with the EC50 of 17.6ng/ml determined by ELISA. See testing image for detail.
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CCR8 Protein (LTP10029)
  • 5 Units in Stock

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