Human CD155/PVR Protein (LTP10755)

Product Name
Human CD155/PVR Protein (LTP10755)
Catalog Number
LTP10755
Quantity
100ug
Price
$360 In stock
Background
CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
Description
Recombinant Human CD155/PVR Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Trp21-Asn343.
Target
CD155/PVR
Species
Human
Gene/Protein ID
P15151-1
Exact Sequence
Trp21-Asn343
Molecular Weight
The protein has a predicted MW of 61.8 kDa. Due to glycosylation, the protein migrates to 75-100 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human TIGIT, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human CD155, hFc Tag with the EC50 of 49.2ng/ml determined by ELISA (QC Test). The affinity constant of 0.958 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CD155/PVR Protein (LTP10755)
  • 5 Units in Stock

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