| Human CD160 Protein (LTP10887) |
| LTP10887 |
| 100ug |
|
$360 In stock |
| CD160 (also Natural killer cell receptor BY55) is a 27 ? 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. CD160 antigenis a receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells. |
| Recombinant Human CD160 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Gly25-Leu158. |
| CD160 |
| Human |
| O95971 |
| Gly25-Leu158 |
| The protein has a predicted MW of 17.7 kDa. Due to glycosylation, the protein migrates to 27-33 kDa based on the Tris-Bis PAGE result. |
| The affinity constant of 1.2uM as determined in SPR assay (Biacore T200). See testing image for detail. |
| C-His-Avi |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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