| Human CD30/TNFRSF8 Protein (LTP10411) |
| LTP10411 |
| 100ug |
|
$305 In stock |
| The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs). |
| Recombinant Human CD30/TNFRSF8 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Phe19-Lys379. |
| CD30/TNFRSF8 |
| Human |
| P28908-1 |
| Phe19-Lys379 |
| The protein has a predicted MW of 65.2 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on the Tris-Bis PAGE result. |
| Immobilized Human CD30 Ligand, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human CD30, hFc Tag with the EC50 of 8.9ng/ml determined by ELISA. See testing image for detail. |
| C-hFc |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Human CD30/TNFRSF8 Protein (LTP10411)](/peptide-product/images/protein-products/LTP10411/20230206155201.png) |