Human CEACAM-8/CD66b Protein (LTP10569)

Product Name
Human CEACAM-8/CD66b Protein (LTP10569)
Catalog Number
LTP10569
Quantity
100ug
Price
$360 In stock
Background
Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. CD66b is an activation marker for human granulocytes.
Description
Recombinant Human CEACAM-8/CD66b Protein is expressed from Expi293 with His tag at the C-terminal. It contains Gln35-Ser319.
Target
CEACAM-8/CD66b
Species
Human
Gene/Protein ID
NP_001807.2
Exact Sequence
Gln35-Ser319
Molecular Weight
The protein has a predicted MW of 32.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 4.59 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CEACAM-8/CD66b Protein (LTP10569)
  • 5 Units in Stock

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