Human CLEC12A/MICL/CLL-1 Protein (LTP10721)

Product Name
Human CLEC12A/MICL/CLL-1 Protein (LTP10721)
Catalog Number
LTP10721
Quantity
100ug
Price
$519 In stock
Background
CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.
Description
Recombinant Human CLEC12A/MICL/CLL-1 Protein is expressed from Expi293 with hFc tag at the N-terminal. It contains His65-Ala265.
Target
CLEC12A/MICL/CLL-1
Species
Human
Gene/Protein ID
Q5QGZ9-2
Exact Sequence
His65-Ala265
Molecular Weight
The protein has a predicted MW of 50.9 kDa. Due to glycosylation, the protein migrates to 68-73 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human CLEC12A, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-CLEC12A Antibody, hFc Tag with the EC50 of 20.2ng/ml determined by ELISA. See testing image for detail.
Tag
N-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CLEC12A/MICL/CLL-1 Protein (LTP10721)
  • 5 Units in Stock

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