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| Human DKK3 Protein (LTP10907) |
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| LTP10907 |
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| 100ug |
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$406 In stock |
| Dkk-3, also known as REIC (Reduced Expansion in Immortalized Cells), is one of four numbered members of the Dickkopf family of Wnt antagonists.DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
| Recombinant Human DKK3 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Pro23-Ile350. |
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| DKK3 |
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| Human |
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| Q9UBP4 |
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| Pro23-Ile350 |
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| The protein has a predicted MW of 39.5 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on the Tris-Bis PAGE result. |
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| 0 |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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