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| Human DLL3 Protein (LTP10756) |
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| LTP10756 |
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| 100ug |
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$450 In stock |
| Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). |
| Recombinant Human DLL3 is expressed from Expi293 with His tag at the N-terminal. It contains Ala27-Arg490. |
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| DLL3 |
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| Human |
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| Q9NYJ7-1 |
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| Ala27-Arg490 |
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| The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human DLL3, His Tag at 0.1ug/mL (100ul/well). Dose response curve for Anti- DLL3 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.22 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| N-His |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS, 200mM Arginine (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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