Human FGFR2 beta (IIIc) Protein (LTP10678)

Product Name
Human FGFR2 beta (IIIc) Protein (LTP10678)
Catalog Number
LTP10678
Quantity
100ug
Price
$519 In stock
Background
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha  isoform, or only IgII and IgIII, referred to as the beta  isoform.
Description
Recombinant Human FGFR2 beta (IIIc) Protein is expressed from Expi293 with His tag at the C-terminal. It contains Arg152-Glu377.
Target
FGFR2 beta (IIIc)
Species
Human
Gene/Protein ID
P21802-1
Exact Sequence
Arg152-Glu377
Molecular Weight
The protein has a predicted MW of 26.4 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human FGFR2 beta (IIIc) Protein (LTP10678)
  • 5 Units in Stock

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