Human GHR/Growth Hormone R Protein (LTP10560)

Product Name
Human GHR/Growth Hormone R Protein (LTP10560)
Catalog Number
LTP10560
Quantity
100ug
Price
$406 In stock
Background
Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.
Description
Recombinant Human GHR/Growth Hormone R Protein is expressed from Expi293 with His tag at the C-terminal. It contains Ala27-Tyr264.
Target
GHR/Growth Hormone R
Species
Human
Gene/Protein ID
P10912-1
Exact Sequence
Ala27-Tyr264
Molecular Weight
The protein has a predicted MW of 28.8 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human GHR/Growth Hormone R Protein (LTP10560)
  • 5 Units in Stock

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