Human GM-CSF R alpha Protein (LTP10543)

Product Name
Human GM-CSF R alpha Protein (LTP10543)
Catalog Number
LTP10543
Quantity
100ug
Price
$406 In stock
Background
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua.
Description
Recombinant Human GM-CSF R alpha Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Glu23-Gly320.
Target
GM-CSF R alpha
Species
Human
Gene/Protein ID
P15509-1
Exact Sequence
Glu23-Gly320
Molecular Weight
The protein has a predicted MW of 63.5 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human GM-CSF at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human GM-CSF R alpha, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human GM-CSF R alpha Protein (LTP10543)
  • 5 Units in Stock

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