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| Human IL-1 Rrp2/IL-1 R6 Protein (LTP10906) |
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| LTP10906 |
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| 100ug |
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$406 In stock |
| The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL?1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL?1 (TIGIRR?2/IL?1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. |
| Recombinant Human IL-1 Rrp2/IL-1 R6 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Asp20-Arg335. |
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| IL-1 Rrp2/IL-1 R6 |
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| Human |
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| Q9HB29-1 |
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| Asp20-Arg335 |
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| The protein has a predicted MW of 39.1 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human IL-1 Rrp2, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Anti-IL-1Rrp2 Antibody, hFc Tag with the EC50 of 24.2ng/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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