Human IL-22 Protein (LTP10539)

Product Name
Human IL-22 Protein (LTP10539)
Catalog Number
LTP10539
Quantity
100ug
Price
$450 In stock
Background
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
Description
Recombinant Human IL-22 Protein is expressed from Expi293 with His tag at the N-terminal. It contains Ala34-Ile179.
Target
IL-22
Species
Human
Gene/Protein ID
Q9GZX6
Exact Sequence
Ala34-Ile179
Molecular Weight
The protein has a predicted MW of 17.8 kDa. Due to glycosylation, the protein migrates to 28-40 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human IL-22, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA (QC Test). See testing image for detail.
Tag
N-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human IL-22 Protein (LTP10539)
  • 5 Units in Stock

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