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| Human IL-3 R alpha/CD123 Protein (LTP10709) |
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| LTP10709 |
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| 100ug |
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$473 In stock |
| Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. |
| Recombinant Human IL-3 R alpha/CD123 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Thr19-Arg305. |
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| IL-3 R alpha/CD123 |
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| Human |
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| P26951-1 |
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| Thr19-Arg305 |
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| The protein has a predicted MW of 59.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human IL-3, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-3 R alpha, hFc Tag with the EC50 of 42.7ng/ml determined by ELISA. See testing image for detail. |
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| C-hFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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