| Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (LTP10163) |
| LTP10163 |
| 100ug |
|
$563 In stock |
| The ?2?1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the ?2?1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis. |
| Recombinant Human Integrin alpha 2 beta 1(ITGA2&ITGB1) Heterodimer Protein is expressed from Expi293 with His tag at the C-terminal. It contains Tyr30-T1132(ITGA2)&Gln21-Asp728(ITGB1). |
| Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer |
| Human |
| P17301-1(ITGA2)&P05556(ITGB1) |
| Tyr30-T1132(ITGA2) & Gln21-Asp728(ITGB1) |
| The protein has a predicted MW of 126.6 kDa(ITGA2)&83.2 kDa(ITGB1). Due to glycosylation, the protein migrates to 110-140 kDa based on the Tris-Bis PAGE result. |
| 0 |
| C-His |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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