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| Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein (LTP10871) |
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| LTP10871 |
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| 100ug |
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$563 In stock |
| Integrin alpha 5/ beta 1, also known as VLA-5, is a widely expressed non-covalent heterodimer of a 160 kDa alpha 5 and a 130 kDa beta 1 Integrin subunit.Alpha 5/ beta 1 is up?regulated on tumor vasculature and promotes angiogenesis. |
| Recombinant Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Phe42-Tyr995(ITGA5) acidic tail&Gln21-Asp728(ITGB1) basic tail. |
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| Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer |
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| Human |
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| P08648(ITGA5)&P05556-1(ITGB1) |
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| Phe42-Tyr995(ITGA5)acidic tail & Gln21-Asp728(ITGB1)basic tail |
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| The protein has a predicted MW of 111.8 kDa (ITGA5)&83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 100-140 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human ITGA5&ITGB1, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGA5&ITGB1 Antibody, hFc Tag with the EC50 of 25.8ng/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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