| Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (LTP10873) |
| LTP10873 |
| 100ug |
|
$563 In stock |
| ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling. |
| Recombinant Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Phe31-Val992(ITGAV) acidic tail&GLy27-Asp718(ITGB3) basic tail. |
| Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer |
| Human |
| P06756-1(ITGAV)&P05106-1(ITGB3) |
| Phe31-Val992(ITGAV)acidic tail & Gly27-Asp718(ITGB3)basic tail |
| The protein has a predicted MW of 114 kDa (ITGAV)&81.3 kDa (ITGB3). Due to glycosylation,the protein migrates to 85-140 kDa based on the Tris-Bis PAGE result. |
| Immobilized Human ITGAV&ITGB3, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 9.2ng/ml determined by ELISA. See testing image for detail. |
| C-His-Avi |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (LTP10873)](/peptide-product/images/protein-products/LTP10873/20221212191613.png) |