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| Human Integrin alpha V beta 5 (ITGAV&ITGB5) Heterodimer Protein (LTP10874) |
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| LTP10874 |
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| 100ug |
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$563 In stock |
| Integrin ITGAV & ITGB5 is a type of integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. However, it inhibits angiogenesis. It consists of two components, integrin alpha V and integrin beta 5. Integrin ITGAV & ITGB5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.(Microbial infection) Integrin ITGAV & ITGB5 acts as a receptor for adenovirus type C. |
| Recombinant Human Integrin alpha V beta 5 (ITGAV&ITGB5) Heterodimer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Phe31-Val992(ITGAV) acidic tail&Gly24-Asn719(ITGB5) basic tail. |
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| Integrin alpha V beta 5 (ITGAV&ITGB5) Heterodimer |
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| Human |
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| P06756-1(ITGAV)&P18084(ITGB5) |
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| Phe31-Val992(ITGAV)acidic tail & Gly24-Asn719(ITGB5)basic tail |
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| The protein has a predicted MW of 114 kDa (ITGAV)&81.4 kDa (ITGB5). Due to glycosylation,the protein migrates to 85-140 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human ITGAV&ITGB5, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-alpha V Antibody, hFc Tag with the EC50 of 7.1ng/ml determined by ELISA. See testing image for detail. |
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| C-His-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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