Human Mature TGF beta 3 Protein (LTP10714)

Product Name
Human Mature TGF beta 3 Protein (LTP10714)
Catalog Number
LTP10714
Quantity
100ug
Price
$609 In stock
Background
Transforming growth factor-beta 3 is a cytokine which is involved in cell growth regulation and differentiation, stimulation of extracellular matrix and modulation of immune responses. TGF beta 3 RNA is expressed in a diverse array of tissues including perichondrium, bone, intervertebral discs, mesenteries, pleura, heart, lung, palate, and amnion, as well as in central nervous system (CNS) structures such as the meninges, choroid plexus and the olfactory bulbs. Furthermore, in several organ systems, TGF beta 3 transcripts are expressed during periods of active morphogenesis suggesting that the protein may be an important factor for the growth and differentiation of many embryonic tissues.
Description
Recombinant Human Mature TGF beta 3 Protein is expressed from Expi293 without tag. It contains Ala301-Ser412.
Target
Mature TGF beta 3
Species
Human
Gene/Protein ID
P10600-1
Exact Sequence
Ala301-Ser412
Molecular Weight
The protein has a predicted MW of 12.7 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human Mature TGF beta 3, No Tag at 1ug (100ul/Well) on the plate. Dose response curve for Human TGF-beta RII, hFc Tag with the EC50 of 15.3ng/ml determined by ELISA. See testing image for detail.
Tag
No Tag
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in 4mM HCl. Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in 4mM HCl.

Image
Human Mature TGF beta 3 Protein (LTP10714)
  • 5 Units in Stock

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