Human MCP-1/CCL2 Protein (LTP10979)

Product Name
Human MCP-1/CCL2 Protein (LTP10979)
Catalog Number
LTP10979
Quantity
100ug
Price
$406 In stock
Background
Monocyte chemotactic protein-1 (MCP-1) (also referred to as chemokine (C-C motif) ligand 2 (CCL2) is expressed by mainly inflammatory cells and endothelial cells. MCP-1 has been reported to play an important role in the pathogenesis of atherosclerosis and considerable evidence supports that the monocyte containing MCPs and macrophage influences the growth of other cell types within the atherosclerotic lesion. This review will focus on the general structure features of MCP-1 and its role in atherosclerosis.
Description
Recombinant Human MCP-1/CCL2 is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Gln24-Thr99.
Target
MCP-1/CCL2
Species
Human
Gene/Protein ID
P13500
Exact Sequence
Gln24-Thr99
Molecular Weight
The protein has a predicted MW of 11.5 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human MCP-1/CCL2 Protein (LTP10979)
  • 5 Units in Stock

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