| Human NKG2A&CD94 Protein (LTP10394) |
| LTP10394 |
| 100ug |
|
$473 In stock |
| The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies. |
| Recombinant Human NKG2A&CD94 Protein is expressed from Expi293 with hFc tag and Flag tag at the N-terminal. It contains Arg100-Leu233(NKG2A)&Ser34-Ile179(CD94). |
| NKG2A&CD94 |
| Human |
| P26715-1(NKG2A)&Q13241-1(CD94) |
| Arg100-Leu233(NKG2A) & Ser34-Ile179(CD94) |
| The protein has a predicted MW of 41.1 kDa (NKG2A)&17.9 kDa (CD94). Due to glycosylation, the protein migrates to 55-65 kDa based on the Tris-Bis PAGE result. |
| Immobilized Human NKG2A&CD94, hFc Tag at 2ug/ml (100ul/Well) on Fc Antibody (2ug/ml) precoated plate. Dose response curve for Biotinylated Anti-NKG2A Antibody, hFc Tag with the EC50 of 40.8ng/ml determined by ELISA. See testing image for detail. |
| N-hFc-Flag |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| ![Human NKG2A&CD94 Protein (LTP10394)](/peptide-product/images/protein-products/LTP10394/20220711140019.png) |