Human NKG2C&CD94 Protein (LTP10971)

Product Name
Human NKG2C&CD94 Protein (LTP10971)
Catalog Number
LTP10971
Quantity
100ug
Price
$473 In stock
Background
NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.
Description
Recombinant Human NKG2C&CD94 Protein is expressed from Expi293 with His tag and Avi tag at the N-terminal. It contains Glu98-Leu231(NKG2C)&Ser34-Ile179(CD94).
Target
NKG2C&CD94
Species
Human
Gene/Protein ID
P26717(NKG2C)&Q13241-1(CD94)
Exact Sequence
Glu98-Leu231(NKG2C) & Ser34-Ile179(CD94)
Molecular Weight
The protein has a predicted MW of 15.3kDa (NKG2C)&17.9kDa (CD94). Due to glycosylation, the protein migrates to 30-50 kDa based on the Tris-Bis PAGE result.
Activity
The affinity constant of 1.65 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Tag
N-His-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human NKG2C&CD94 Protein (LTP10971)
  • 5 Units in Stock

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