| Human NKG2C&CD94 Protein (LTP10971) |
| LTP10971 |
| 100ug |
|
$473 In stock |
| NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion. |
| Recombinant Human NKG2C&CD94 Protein is expressed from Expi293 with His tag and Avi tag at the N-terminal. It contains Glu98-Leu231(NKG2C)&Ser34-Ile179(CD94). |
| NKG2C&CD94 |
| Human |
| P26717(NKG2C)&Q13241-1(CD94) |
| Glu98-Leu231(NKG2C) & Ser34-Ile179(CD94) |
| The protein has a predicted MW of 15.3kDa (NKG2C)&17.9kDa (CD94). Due to glycosylation, the protein migrates to 30-50 kDa based on the Tris-Bis PAGE result. |
| The affinity constant of 1.65 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
| N-His-Avi |
| Expi293 |
| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Less than 1EU per ug by the LAL method. |
| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipped at ambient temperature. |
| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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