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| Human PSMA/FOLH1 Protein (LTP10519) |
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| LTP10519 |
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| 100ug |
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$473 In stock |
| Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. |
| Recombinant Human PSMA/FOLH1 Protein is expressed from Expi293 with hFc tag at the N-terminal. It contains Lys44-Ala750. |
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| PSMA/FOLH1 |
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| Human |
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| Q04609-1 |
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| Lys44-Ala750 |
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| The protein has a predicted MW of 106.8 kDa. Due to glycosylation, the protein migrates to 110-120 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human PSMA, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-PSMA Antibody, hFc Tag with the EC50 of 14.3ng/ml determined by ELISA. See testing image for detail. |
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| N-hFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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