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| Human TGF-beta RII/TGFBR2 Protein (LTP10974) |
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| LTP10974 |
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| 100ug |
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$450 In stock |
| The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-?) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. |
| Recombinant Human TGF-beta RII/TGFBR2 Protein is expressed from Expi293 with hFc tag at the N-terminal. It contains Ile24-Asp159. |
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| TGF-beta RII/TGFBR2 |
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| Human |
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| P37173-1 |
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| Ile24-Asp159 |
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| The protein has a predicted MW of 44.2 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human Mature TGF beta 1 at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human TGF-beta RII, hFc Tag with the EC50 of 23.2ng/ml determined by ELISA. See testing image for detail. |
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| N-hFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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