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| Human TGFBR1 Protein (LTP11108) |
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| LTP11108 |
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| 100ug |
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$440 In stock |
| transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR?98?5p. miR?98?5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. |
| Recombinant Human TGFBR1 Protein is expressed from Expi293 with mFc (IgG1) tag and Avi tag at the C-terminal. It contains Leu34-Glu125. |
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| TGFBR1 |
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| Human |
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| P36897-1 |
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| Leu34-Glu125 |
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| The protein has a predicted MW of 38.2 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on the Tris-Bis PAGE result. |
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| The affinity constant of 0.35 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
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| C-mFc-Avi |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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