Human TROP-2/TACSTD2 Protein (LTP11079)
LTP11079
100ug
$ 270 In stock
Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Recombinant Human TROP-2/TACSTD2 Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains His27-Thr274.
TROP-2/TACSTD2
Human
P09758
His27-Thr274
The protein has a predicted MW of 54.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on the Tris-Bis PAGE result.
Immobilized Human TROP-2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-TROP-2 Antibody, hFc Tag with the EC50 of 7.7ng/ml determined by ELISA. See testing image for detail.
C-hFc
Expi293
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Less than 1EU per ug by the LAL method.
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Shipped at ambient temperature.
Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.