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| Human VEGF R2/KDR Protein (LTP11111) |
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| LTP11111 |
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| 100ug |
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$360 In stock |
| Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. |
| Recombinant Human VEGF R2/KDR Protein is expressed from Expi293 with mFc (IgG1) tag at the C-terminal. It contains Ala20-Glu764. |
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| VEGF R2/KDR |
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| Human |
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| P35968-1 |
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| Ala20-Glu764 |
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| The protein has a predicted MW of 110 kDa. Due to glycosylation, the protein migrates to 150-200 kDa based on the Tris-Bis PAGE result. |
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| Immobilized Human VEGF165 1ug/ml (100ul/Well) on the plate. Dose response curve for Human VEGF R2, mFc Tag with the EC50 of 42.3ng/ml determined by ELISA. See testing image for detail. |
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| C-mFc |
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| Expi293 |
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| > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
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| Less than 1EU per ug by the LAL method. |
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| Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization. |
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| Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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| Shipped at ambient temperature. |
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| Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
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